Supporting Information Genome-wide fine-scale recombination rate variation in Drosophila melanogaster
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چکیده
Text S1 Two-locus recursion relation Suppose we sample n haplotypes, observing their alleles at each of two loci and obtaining configuration n = (a, b, c). Here c = (cij) is a matrix of the counts of haplotypes for which both alleles were observed; cij is the number of haplotypes with allele i at the first locus and allele j at the second locus. We also allow for the possibility that a haplotype had data missing at one locus: a = (ai)i=1...,K is the vector of counts of haplotypes with allele i observed at the first locus and missing data at the second locus, and b = (bj)j=1,...,L is the vector of counts of haplotypes with allele j observed at the second locus and missing data at the first locus. Further, let: a = K ∑
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